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        231-240 of 846 results for 'early lung health'

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        Research

        Mucopolysaccharidosis (MPS IIIA) mice have increased lung compliance and airway resistance, decreased diaphragm strength, and no change in alveolar structure

        Mucopolysaccharidosis type IIIA (MPS IIIA) is characterized by neurological and skeletal pathologies caused by reduced activity of the lysosomal hydrolase, sulfamidase, and the subsequent primary accumulation of undegraded heparan sulfate (HS). Respiratory pathology is considered secondary in MPS IIIA and the mechanisms are not well understood.  ...

        Research

        Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

        Standards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers ...

        Research

        Exhaled breath temperature in healthy children is influenced by room temperature and lung volume

        Exhaled breath temperature (EBT) has been proposed for the non-invasive assessment of airway inflammation ...

        Research

        Evaluation of the implementation and clinical effects of an intervention to improve medical follow-up and health outcomes for Aboriginal children hospitalised with chest infections

        Aboriginal children hospitalised with acute lower respiratory infections (ALRIs) are at-risk of developing bronchiectasis, which can progress from untreated protracted bacterial bronchitis, often evidenced by a chronic (>4 weeks) wet cough following discharge. We aimed to facilitate follow-up for Aboriginal children hospitalised with ALRIs to provide optimal management and improve their respiratory health outcomes. ...

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        Fellowship to support research into ways to improve the lung health of people born preterm

        Wal-yan Respiratory Research Centre researcher Ms Denby Evans has been awarded one of four inaugural fellowships supported by the State's Future Health Research and Innovation (FHRI) Fund and Brightspark Foundation, enabling her to further her research into ways to improve the lung health of people ...

        Research

        Mouse Lung Structure and Function after Long-Term Exposure to an Atmospheric Carbon Dioxide Level Predicted by Climate Change Modeling

        Climate change models predict that atmospheric carbon dioxide [CO2] levels will be between 700 and 900 ppm within the next 80yrs. In this study we aimed to assess the respiratory structure and function effects of long-term exposure to 890ppm CO2 from preconception to adulthood using a mouse model. ...

        Research

        The association between Staphylococcus aureus and subsequent bronchiectasis in children with cystic fibrosis

        De novo S. aureus acquisition at age 3 is associated with later bronchiectasis and FEF25-75 in children with CF ...

        Research

        Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis

        Our data associates IL-1α with early structural lung damage in CF and suggests this pathway as a novel anti-inflammatory target ...

        Research

        Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells

        Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces. ...

        Research

        An introduction to clinical trial design

        This manuscript will give a brief overview of clinical trial design including the strengths and limitations of various approaches ...

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