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        News & Events

        New policy provides much needed focus on overlooked youth

        The need for a WA Youth Health Policy has been evident for years. Now, with the Telethon Kids Institute helping to drive the project, it is coming to fruition. ...

        News & Events

        Call for Group A streptococcal infections to become notifiable diseases

        Researchers at the Telethon Kids Institute say Group A Streptococcus should become a nationally notifiable disease in Australia. ...

        News & Events

        National honour for infectious diseases researcher

        Perth researcher dedicated to reducing serious chest and ear infections in children has been recognised with the award of Officer in the Order of Australia ...

        News & Events

        The science of immunisation: Questions and answers

        Common myths about immunisation have been laid to rest in a new booklet written by top immunologists and published by the Australian Academy of Science. ...

        News & Events

        Exposure to sunlight could reduce asthma

        Australian researchers have found that exposure to measured doses of ultraviolet light, such as sunlight, could reduce asthma. ...

        Investigators and Project Team

        Ainslie Keerthi Christine Investigators Project Team Poore Anpalagan Everest . Prof Jonathan Carapetis Telethon Kids Institute Clinical, Epidemiology ...

        Research

        What does better look like in individuals with severe neurodevelopmental impairments? A qualitative descriptive study on SCN2A-related developmental and epileptic encephalopathy

        There are limited psychometric data on outcome measures for children with Developmental Epileptic Encephalopathies (DEEs), beyond measuring seizures, and no data to describe meaningful change. This study aimed to explore parent perceptions of important differences in functional abilities that would guide their participation in clinical trials. ...

        Research

        FDA Patient-Focused Drug Development Guidances: Considerations for Trial Readiness in Rare Developmental and Epileptic Encephalopathies

        Developmental and epileptic encephalopathies (DEE) are rare, often monogenic neurodevelopmental conditions. Most affected individuals have refractory seizures. All have multiple severe impairments which can be as life-limiting as or more limiting than the seizures themselves. Mechanism- and gene-targeted therapies for these individually rare, genetic conditions hold hope for treatment, amelioration of disease expression, and even cure.  ...

        Research

        Unraveling the Optimum Latent Structure of Attention-Deficit/Hyperactivity Disorder: Evidence Supporting ICD and HiTOP Frameworks

        Attention Deficit/hyperactivity disorder (ADHD) is conceptualized differently in the Diagnostic and Statistical Manual (DSM-5), the International Classification of Diseases-10 (ICD-10), and the Hierarchical Taxonomy of Psychopathology (HiTOP) frameworks. This study applied independent cluster confirmatory factor analysis (ICM-CFA), exploratory structure equation model with target rotation (ESEM), and the S-1 bi-factor CFA approaches to evaluate seven ADHD models yielded by different combinations of these taxonomic frameworks. ...

        Research

        Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

        Standards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers ...

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