Specialized Proresolving Lipid Mediators are increased after 8 weeks n-3 fatty acid supplementation in patients with chronic kidney disease ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

The increase in childhood allergic disease in recent decades has coincided with increased folic acid intakes during pregnancy. Circulating unmetabolized folic acid (UMFA) has been proposed as a biomarker of excessive folic acid intake. We aimed to determine if late-pregnancy serum UMFA and total folate concentrations were associated with allergic disease risk in the offspring at 1 y of age in a population at high risk of allergy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Preterm babies have a heightened risk of infection as their immune system is not mature. The Neonatal Health Team is exploring new ways to diagnose, prevent and treat infections in WA's smallest patients . ...

• Telethon Kids Institute
• Our research
• Early Environment
• Early Life & Life-Course Health

Debbie Susan Palmer Prescott D SL BSc BND PhD MBBS BMedSci PhD FRACP Head, Early Life & Life-Course Health Program; Team Lead, Nutrition in Early ...

• Telethon Kids Institute
• Projects
• Past projects

Repurposed drugs with host-directed antiviral and immunomodulatory properties have shown promise in the treatment of COVID-19, but few trials have studied combinations of these agents. The aim of this trial was to assess the effectiveness of affordable, widely available, repurposed drugs used in combination for treatment of COVID-19, which may be particularly relevant to low-resource countries.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

There is a growing need for early biomarkers that may predict the development of atopic dermatitis (AD). As alterations in skin barrier may be a primary event in disease pathogenesis, epithelial cell (EC) cytokines expression patterns may be a potential biomarker in early life to target allergy preventive strategies towards "at-risk" infants. The aim of this longitudinal investigation was to examine from birth over the course of infancy levels of the EC cytokines: thymic stromal lymphopoietin (TSLP), interleukin (IL)-33, IL-25, and IL-17 in infants at high-risk of AD due to maternal atopy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Food allergies have become more common in our community, with up to one in ten young children now affected. Reactions can range from mild rashes to life threatening anaphylaxis and breathing difficulties. The most common food allergies are to egg, peanut, tree nuts, cow’s milk, fish, shellfish, wheat and soy. ...

• Telethon Kids Institute
• Our research
• Research Topics

High consumption of sugar sweetened beverages (SSBs) has been linked to unhealthy weight gain and nutrition related chronic disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011