BCG vaccination and revaccination are increasingly being considered for the protection of adolescents and adults against tuberculosis and, more broadly, for the off-target protective immunological effects against other infectious and noninfectious diseases. Within an international randomized controlled trial of BCG vaccination in healthcare workers (the BRACE trial), we evaluated the incidence of local and serious adverse events, as well as the impact of previous BCG vaccination on local injection site reactions (BCG revaccination). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

To evaluate the safety and immunogenicity of V114 [15-valent pneumococcal conjugate vaccine (PCV) containing serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9 V, 14, 18C, 19A, 19F, 22F, 23F, 33F], followed by 23-valent pneumococcal polysaccharide vaccine (PPSV23) 8 weeks later, in children with HIV. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Individuals who receive allogeneic hematopoietic cell transplant (allo-HCT) are immunocompromised and at high risk of pneumococcal infections, especially in the months following transplant. This study evaluated the safety and immunogenicity of V114 (VAXNEUVANCE; Merck, Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., Rahway, NJ, USA), a 15-valent pneumococcal conjugate vaccine (PCV), when given to allo-HCT recipients.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

There is a wide spectrum of disease severity in paediatric Staphylococcus aureus bacteraemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Increased collaboration and engagement across all sectors can optimise the use of linked data to help reduce the burden of infectious diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Preterm infants are at a high risk of developing late-onset sepsis (LOS). Lactoferrin is one of the most abundant endogenous antimicrobial proteins expressed in breast milk, stools, and blood, and a candidate for preventive intervention. Large clinical trials have recently investigated whether enteral supplementation with bovine lactoferrin reduces LOS. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

We assessed the safety of receiving an influenza vaccination during any trimester of pregnancy with respect to preterm births and infant birthweight. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

Intervention to address young people's low levels of understanding, to promote their involvement in consent and reduce vaccination-related fear and anxiety. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

Chart review to validate linked microbiological data ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Developed a specific Haemophilus influenzae quantitative PCR (qPCR) that also identifies fucose-negative and protein D-negative strains ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016