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        261-270 of 1322 results for '2010'

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        Research

        Meningococcal serogroup B-specific responses after vaccination with bivalent rLP2086

        Assessment of the persistence of bactericidal antibodies up to 4 years after a three-dose schedule of bivalent rLP2086 ...

        Research

        Randomised controlled trials in cystic fibrosis: What, when and how?

        The major morbidity and mortality from cystic fibrosis (CF) comes from progressive lung disease with bronchiectasis leading to respiratory failure ...

        Research

        Antimicrobial susceptibility of Moraxella catarrhalis isolated from children in Kalgoorlie-Boulder

        To investigate antimicrobial susceptibility of Moraxella catarrhalis isolated from a cohort of children being followed in a study of the natural history of OM ...

        Research

        The Second Research Report: patterns and trends in mortality of Western Australian infants, children and young people 2004-2005

        This report was commissioned by the Department for Child Protection as an ongoing initiative to continue the work initiated by researchers at the Telethon Kids ...

        Research

        Prevalence of tracheobronchomalacia is higher than previously reported in children with cystic fibrosis

        Tracheobronchomalacia (TBM) is estimated to be present in 1 in 2100 children. Previous reports suggest the prevalence is higher in children with cystic fibrosis (CF). This has clinical implications with potential to influence airway clearance and lung health. ...

        Research

        Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial

        There has been renewed interest in the therapeutic use of bacteriophages (phages); however, standardised therapeutic protocols are lacking, and there is a paucity of rigorous clinical trial data assessing efficacy. ...

        Research

        The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial

        Structural lung disease and neutrophil-dominated airway inflammation is present from 3 months of age in children diagnosed with cystic fibrosis after newborn screening. We hypothesised that azithromycin, given three times weekly to infants with cystic fibrosis from diagnosis until age 36 months, would reduce the extent of structural lung disease as captured on chest CT scans. ...

        Research

        An eight-plex immunoassay for Group A streptococcus serology and vaccine development

        Group A Streptococcus (GAS) is a major human pathogen responsible for superficial infections through to life-threatening invasive disease and the autoimmune sequelae acute rheumatic fever (ARF). Despite a significant global economic and health burden, there is no licensed vaccine available to prevent GAS disease. Several pre-clinical vaccines that target conserved GAS antigens are in development. ...

        Research

        QuantSeq. 3′ Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis

        QuantSeq, coupled with a fast quantification method such as Salmon, should provide a viable alternative to traditional RNA-Seq in many applications ...

        Research

        Geo-visual integration of health outcomes and risk factors using excess risk and conditioned choropleth maps

        Ghana remains a malaria hyperendemic region with district-level spatial heterogeneity ...

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