These data provide proof of concept supporting the rationale for developing transplacental immune reprogramming approaches for primary disease prevention ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice a maternal low-fiber diet led to enhanced LRI severity in infants because of delayed plasmacytoid dendritic cell recruitment and perturbation of regulatory T cell expansion in the lungs. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Findings by Professor Pat Holt revealed researchers had been heading down the wrong path in their battle strategy against respiratory allergy and asthma. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2015
• June

In the present study, we sought to evaluate the complement activation product C4d as a marker for lupus nephritis in systemic lupus erythematosus (SLE). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

The burden of IgE-mediated food allergy in Australian born children is reported to be among the highest globally. This illness shares risk factors and frequently coexists with asthma, one of the most common noncommunicable diseases of childhood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

This study analyzed autoantibodies to complement factor H (FH) in 2 independent cohorts of patients with antiphospholipid syndrome. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

This chapter deals with asbestos-related non-malignant pleural disease and mesothelioma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• August 2016

the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Children are more vulnerable than adults to climate-related health threats, but reviews examining how climate change affects human health have been mainly descriptive and lack an assessment of the magnitude of health effects children face. This is the first systematic review and meta-analysis that identifies which climate-health relationships pose the greatest threats to children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024