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        Research Project Manager - ARF (Acute Rheumatic Fever)

        This position will be responsible for managing the NHMRC funded project, Towards a Diagnostic Test for Rheumatic Fever, and related studies, and ...

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        Timo Lassmann

        Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology ...

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        Research

        Reference exome data for a Northern Brazilian population

        Exome sequencing is widely used in the diagnosis of rare genetic diseases and provides useful variant data for analysis of complex diseases. There is not always adequate population-specific reference data to assist in assigning a diagnostic variant to a specific clinical condition. ...

        Research

        Reference genotype and exome data from an Australian Aboriginal population for health-based research

        This data set provides a useful reference point for genomic studies on Aboriginal Australians ...

        Research

        Zika Virus Changes Methylation of Genes Involved in Immune Response and Neural Development in Brazilian Babies Born With Congenital Microcephaly

        The recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation. ...

        Research

        A community-led, trauma-informed psychosocial intervention to improve health outcomes of children and young people with Type-1 diabetes

        Alix Helen Keely Rigel Nicole Woolard Milroy Bebbington Paciente Wickens AW HM KB RP NW BPsych (Hons), PhD MBBS; FRANZCP; CATCAP MClinPsych/PhD MPH ( ...

        Research

        Perspectives of LGBTQA+ young people on suicide prevention services in Australia

        LGBTQA + people are less likely to access mental health care despite an increased risk of adverse mental health outcomes including suicidal thoughts and behaviours. The present study aimed to explore Australian LGBTQA + young people's perceptions of key factors associated with access to suicide prevention services. ...

        Research

        Powerful promotions: An investigation of the teen-directed marketing power of outdoor food advertisements located near schools in Australia

        Adolescents are heavily exposed to unhealthy outdoor food advertisements near schools, however, the marketing power of these advertisements among adolescents has not yet been explored. This study aimed to investigate the teen-directed marketing features present and quantify the overall marketing power of outdoor food advertisements located near schools to explore any differences by content (ie, alcohol, discretionary, core and miscellaneous foods) school type (ie, primary, secondary, K-12) and area-level socio-economic status (SES; ie, low vs high). ...

        Research

        P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages

        The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte ...

        Coordinator, Pilbara FASD Prevention Project

        This role will be based in the Telethon Kids Pilbara office in South Hedland and will require extensive and regular travel to 3 research sites that ...

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