Population-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Asthma is a chronic disease of the airways, most commonly driven by immuno-inflammatory responses to ubiquitous airborne antigens. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

The aim of this study was to use total-population based data on an otherwise healthy population of children to assess the relationship between early... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

This article assesses the absolute and specific antibody titres to VP1 antigens of the gut-trophic enteroviruses, echovirus 30 and Sabin 1 poliovirus, in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

Young adulthood is a critical life period for health and health behaviours. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

There is substantial interest in studying lung function in infants, to better understand the early life origins of chronic lung diseases such as asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The prevalence of IgE binding to the group 15 and 18 house dust mite (HDM) allergens of the Dermatophagoides species... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• October 2012

Intrauterine growth restriction (IUGR) is associated with asthma. Murine models of IUGR have altered airway responsiveness in the absence of any inflammatory exposure. Given that a primary feature of asthma is airway inflammation, IUGR-affected individuals may develop more substantial respiratory impairment if subsequently exposed to an allergen. This study used a maternal hypoxia-induced mouse model of IUGR to determine the combined effects of IUGR and allergy on airway responsiveness. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021