Emily Terrance Anya Brittany Fletcher Johns Jones Dewdney EF T AJ BD BSc (Hons) MRes PhD BSc MSc PhD BSc, MBSc, PhD Senior Research Fellow Honorary ...

• Telethon Kids Institute
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Standard-risk WNT medulloblastoma patients have an excellent prognosis using the combination of standard dose craniospinal radiotherapy (CSI) followed by platinum and alkylator based chemotherapy. A recent pilot study that attempted to completely omit radiotherapy was terminated early as all patients relapsed rapidly. The study highlights that therapy is the most important prognostic factor, with CSI still required to cure even the most favorable subgroup of medulloblastoma patients.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• December 2023

Children with Down syndrome (DS, trisomy 21) are at a significantly higher risk of developing acute leukemia compared to the overall population. Many studies investigating the link between trisomy 21 and leukemia initiation and progression have been conducted over the last two decades. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Acute erythroleukemia (AEL or acute myeloid leukemia [AML]-M6) is a rare but aggressive hematologic malignancy. Previous studies showed that AEL leukemic cells often carry complex karyotypes and mutations in known AML-associated oncogenes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Medulloblastoma (MB) is the most common malignant brain tumor in children and a leading cause of cancer-related mortality and morbidity. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

We identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

Chief Data Scientist ...

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Undescended testes is associated with an increased risk of testicular cancer and male infertility, and decreased paternity ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Nick Gottardo NG MBChB FRACP PhD Co-Head, Brain Tumour Research nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour Research Professor Nick ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021