Brad Carrington Raewyn Carol Melissa Farrant Shepherd Mutch Michie O'Donnell Photos BM CCJ RM C M BSc (Hons), PhD PhD MBChB., DipRACOG., Cert.HPRT, ...

• 1. Telethon Kids Institute
• Projects

Glioblastoma in adults, and medulloblastoma and pineoblastoma that mainly affect children, are aggressive brain tumors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

A Telethon Kids Institute research student concerned by the types of injuries he was seeing in emergency departments as a trainee doctor has spearheaded an Australia-first study. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2021
• May

Brad Carol Glenn Carrington Steve Farrant Michie Pearson Shepherd Zubrick Related Projects Elder Researchers Contact BM C G CCJ SR If you would like ...

• 1. Telethon Kids Institute
• Our research
• Brain and Behaviour
• Mental Health and Youth Program
• Aboriginal Health and Wellbeing

The Australian Technical Advisory Group on Immunisation and New Zealand Ministry of Health recommend all children aged ≥ 5 years receive either of the two mRNA COVID-19 vaccines: Comirnaty (Pfizer), available in both Australia and New Zealand, or Spikevax (Moderna), available in Australia only. Both vaccines are efficacious and safe in the general population, including children. Children and adolescents undergoing treatment for cancer and immunosuppressive therapy for non-malignant haematological conditions are particularly vulnerable, with an increased risk of severe or fatal COVID-19. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Latest blog posts Welcome to the CliniKids Blog! As a parent, it can be hard to navigate the sea of information from professionals, family, friends ...

• CliniKids
• Information hub

Brad Carol Shelley Farrant Michie Gorman Investigators BM C S Andrea Begley Dr Andrea Begley is an advanced accredited practicing dietitian with a ...

• 1. Telethon Kids Institute
• Projects

Telethon Kids' autism research takes place at CliniKids, a centre that integrates world-class research with a clinical service for children with developmental delay and/or autism and their families. Our team of researchers work in partnership with clinicians to give the community access to the world's best evidence-based therapies. ...

• 1. Telethon Kids Institute
• Our research
• Brain and Behaviour
• Development and Disability

The trivalent inactivated influenza vaccine is safe, immunogenic, provides clinical protection and should be administered annually to immunosuppressed children receiving treatment for cancer ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• February 2016