Applied Spatial Statistics used in conjunction with geographic information systems (GIS) provide an efficient tool for the surveillance of diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• February 2010

Genome-wide association studies (GWASs) have been successful at identifying single-nucleotide polymorphisms (SNPs) highly associated with common traits... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• August 2012

We confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• August 2011

Epidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Comparing how mast cells are “programmed” in allergic and non-allergic children at one year of age. ...

• The ORIGINS Project
• Sub-projects
• Allergy, Inflammation & Immunity

Research from Telethon Institute for Child Health Research has shown that children born in modern industrialised environments have more responsive immune ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2012
• August

Infant acute lymphoblastic leukemia (ALL) is characterized by a high incidence of KMT2A gene rearrangements and poor outcome. We evaluated the value of minimal residual disease (MRD) in infants with KMT2A-rearranged ALL treated within the Interfant-06 protocol, which compared lymphoid-style consolidation (protocol IB) versus myeloid-style consolidation (araC, daunorubicin, etoposide/mitoxantrone, araC, etoposide). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Little or large, every donation made to the Telethon Kids Institute is precious. ...

• Giving at Telethon Kids
• Your impact
• Giving stories
• Stories from our Community
• 2017