Pirate Ship Research Fellow ...

• 1. Telethon Kids Institute
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Nick Raelene Gottardo Endersby NG R MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research Brainchild Fellow; Co-Head, Brain Tumour Research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

Medulloblastoma is the most common malignant paediatric brain tumour and a leading cause of cancer-related mortality and morbidity. Existing treatment protocols are aggressive in nature resulting in significant neurological, intellectual and physical disabilities for the children undergoing treatment. Thus, there is an urgent need for improved, targeted therapies that minimize these harmful side effects. ...

• 1. Telethon Kids Institute
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• 2021
• June 2021

Nick Raelene Gottardo Endersby NG R MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research Brainchild Fellow; Co-Head, Brain Tumour Research ...

• 1. Telethon Kids Institute
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Previous preclinical and clinical trials have shown promising antitumour activity and toxicity profile when employing the ‘Synergy between Immunotherapy and Radiotherapy’ (SITAR) strategy. Approximately, one in seven radiation therapy studies currently recruiting is investigating SITAR. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

Are you a parent or caregiver of a child with neurodevelopmental and cognitive concerns, such as ADHD? Are you pregnant and have a family history of ADHD? Then we would welcome you expressing interest in joining our community reference group to, share your thoughts, and help us shape our research strategies to enhance our understanding on nutrition for pregnant and breastfeeding women and child brain development. ...

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Docosahexaenoic acid (DHA) is a component of neural tissue. Because its accretion into the brain is greatest during the final trimester of pregnancy, infants born before 29 weeks' gestation do not receive the normal supply of DHA. The effect of this deficiency on subsequent cognitive development is not well understood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

Nick Raelene Terrance Gottardo Endersby Johns NG R T MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research Brainchild Fellow; Co-Head, Brain ...

• 1. Telethon Kids Institute
• Projects

The mitogen-activated protein kinase (MAPK) pathway signaling pathway is one of the most commonly mutated pathways in human cancers. In particular, BRAF alterations result in constitutive activation of the rapidly accelerating fibrosarcoma-extracellular signal-regulated kinase-MAPK significant pathway, leading to cellular proliferation, survival, and dedifferentiation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

ORIGINS Director, Prof Desiree Silva is playing an integral role in promoting a Thrive by Five TED Talk asking parents to engage more meaningfully and often with children in order to promote their brain development and set them up for life. ...

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