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        Research

        The 2015 Middle Childhood Survey (MCS) of mental health and well-being at age 11 years in an Australian population cohort

        most children report mental health and well-being, but the population distribution spanned the full range of possible scores on every construct. ...

        Research

        The role of preschool quality in promoting child development: evidence from rural Indonesia

        This article examines the relationship between preschool quality and children’s early development in a sample of over 7900 children enrolled in 578 preschools in rural Indonesia. ...

        Research

        Genotype and phenotype spectrum of NRAS germline variants

        Here we describe 19 new cases with RASopathy due to disease-causing variants in NRAS ...

        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        Recent studies based on hospital admissions have reported a significant increase in anaphylaxis prevalence. ...

        Research

        Somatosensory discrimination intervention improves body position sense and motor performance in children with hemiplegic cerebral palsy

        The intervention group improved in goal performance, proprioception, and bimanual hand use and maintained improvement at 6-mo follow-up. ...

        Research

        Clinical development strategy for a candidate group A streptococcal vaccine

        This review outlines a clinical development strategy detailing the phases of development required for registration of a candidate Group A streptococci vaccin ...

        Research

        ‘Is it like one of those infectious kind of things?’ The importance of educating young people about HPV and HPV vaccination at school

        Greater knowledge and understanding of National Human Papillomavirus vaccination appeared to promote positive attitudes towards vaccination ...

        Research

        Pulmonary delivery of virosome-bound antigen enhances antigen-specific CD4+ T cell proliferation compared to liposome-bound or soluble antigen

        Pulmonary administration of biomimetic nanoparticles loaded with antigen may represent an effective strategy to directly modulate adaptive immune responses ...

        Research

        The role of PKCzeta in cord blood T-cell maturation towards Th1 cytokine profile and its epigenetic regulation by fish oil

        Here, we present evidence that there are two major control points to explain the immunodeficiency in CB T-cells, leading to a decreased IFNy synthesis. ...

        Research

        Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

        We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria. ...

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