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        Research

        The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

        Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders. ...

        Research

        Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response

        Despite low ERBB4 mRNA in glioblastoma, the functional effects of increased ERBB4 activation identify ERBB4 as a potential prognostic and therapeutic target ...

        Research

        Do carer’s levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

        The aim of the current study was to determine how carer needs changed longitudinally and understand associations between unmet needs and distress. ...

        Areas of research

        Our research funders Our research is funded by the following grants: National Health and Medical Research Council Project Grant Towards ...

        Global Gut Bacteria in Newborns

        Comparing gut bacteria in newborns from around the world. ...

        News & Events

        Meet Shakara - STARS Award Recipient

        Shakara Liddelow-Hunt secured STARS funding to attend a two-day workshop, Start Talking About Relationships & Sexual Health Training. ...

        Research

        A rapid semi-quantitative screening method to assess chemicals present in heated e-liquids and e-cigarette aerosols

        Electronic cigarettes (e-cigarettes) lack regulatory status as therapeutic products in all jurisdictions worldwide. They are potentially unsafe consumer products, with significant evidence they pose a risk to human health. Therefore, developing rapid, economical test methods to assess the chemical composition of e-liquids in heated and unheated forms and the aerosols produced by e-cigarettes is crucial. ...

        Research

        Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency

        We aimed to investigate the molecular basis underlying a novel phenotype including hypopituitarism associated with primary ovarian insufficiency. ...

        Research

        Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages

        A hallmark of Listeria (L.) monocytogenes pathogenesis is bacterial escape from maturing entry vacuoles, which is required for rapid bacterial replication in the host cell cytoplasm and cell-to-cell spread. The bacterial transcriptional activator PrfA controls expression of key virulence factors that enable exploitation of this intracellular niche. ...

        News & Events

        Researchers tackle big issues in child development

        Perth's Telethon Institute for Child Health Research has been awarded a major national grant to continue ground-breaking work on child health and development. ...

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