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        Research

        Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cells

        The airway epithelium in asthma displays altered repair and incomplete barrier formation. ...

        Research

        END RHD Demonstration Communities

        Glenn Jonathan Rosemary Pearson Carapetis AM Wyber G JR R BA (Education) PhD Candidate AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Director ...

        Research

        “Sometimes Our Mob Don't Really Take It Serious Until It's Serious”: The Experiences of Western Australian Aboriginal Adolescents Living With Type 2 Diabetes, Their Parents, and Their Family Members

        In Australia, Aboriginal children experience disproportionate rates of type 2 diabetes (T2D) compared with non-Aboriginal children. The aim of this qualitative study was to explore the experiences of Aboriginal adolescents with T2D and their family members to better understand the influences of T2D on self-management, with findings used to inform an enhanced service model of care. ...

        Research

        A data infrastructure for improving Aboriginal life pathways: the influence of health, education, child protection and justice systems over time and across generations

        Francis Glenn Steve Sarah Mitrou Pearson Zubrick Johnson FG G SR SJ BEc BA (Education) PhD Candidate FASSA, FAAMHS, MSc AM PhD BA, PostGradDip; PhD ...

        Research

        Genetic Research and Aboriginal and Torres Strait Islander Australians

        Human genetic research promises to deliver a range of health benefits to the population. Here we consider how the different levels of Indigenous research... ...

        Research

        Wellbeing study

        Helen Alix Fiona Nicole Elmie Lisa Rigel Milroy Woolard Wood Wickens Janse Van Rensburg McGivern Paciente HM AW FW NW EJVR LM RP MBBS; FRANZCP; ...

        Research

        Searching for a technology-driven acute rheumatic fever test: the START study protocol

        The absence of a diagnostic test for acute rheumatic fever (ARF) is a major impediment in managing this serious childhood condition. ARF is an autoimmune condition triggered by infection with group A Streptococcus. ...

        Research

        Delivering Elder- and Community-Led Aboriginal Early Childhood Development Research: Lessons from the Ngulluk Koolunga Ngulluk Koort Project

        We describe the application of a participatory action research methodology that is grounded in Aboriginal worldviews ...

        Research

        Exploring quality of life in individuals with a severe developmental and epileptic encephalopathy, CDKL5 Deficiency Disorder

        CDKL5 Deficiency Disorder (CDD) is a rare genetic disorder caused by a mutation in the cyclin-dependent kinase-like 5 (CDKL5) gene. It is now considered to be a developmental and epileptic encephalopathy because of the early onset of seizures in association with severe global delay. Other features include cortical visual impairment, sleep and gastro-intestinal problems. Progress in clinical understanding, especially regarding the spectrum of functional ability, seizure patterns, and other comorbidities was initially slow but accelerated in 2012 with the establishment of the International CDKL5 Database (ICDD). Our aim was to use this data source to investigate quality of life (QOL) and associated factors in this disorder. ...

        Research

        Improving access to primary care for Aboriginal babies in Western Australia: Study protocol for a randomized controlled trial

        A population-based, stepped wedge, cluster randomized controlled trial of an enhanced model of early infant primary care ...

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