Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells through the inhibition of DNA damage repair pathways is a potential therapeutic strategy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Medulloblastoma, the most common pediatric malignant brain tumor, consists of at least four distinct molecular subgroups. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

HealthNuts is a single-centre, multi-wave, population-based longitudinal study designed to assess prevalence, determinants, natural history and allergy... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Researchers at Perth's Telethon Institute are one step closer to preventing serious lung disease which is the main cause of suffering in cystic fibrosis. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2013
• May

The P2X7R is highly expressed on the macrophage cell surface, and activation of infected cells by extracellular ATP has been shown to kill intracellular bacte ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• June 2010

Brain tumors presenting in infancy, especially during the first 6 months of life. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• September 2012

With improvement in leukemia therapy, central nervous system (CNS) tumors are the leading cause of cancer mortality in children and the most expensive... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

To determine the constellation of lifestyle and demographic factors that are associated with poor mental health in an adolescent population. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Fiona Stanley FJ FAA FASSA MSc MD FFPHM FAFPHM FRACP FRANZCOG HonDSc HonDUniv HonFRACGP HonMD HonFRCPCH HonLLB (honoris causa) Patron 08 6319 1176 ...

• 1. Telethon Kids Institute
• Our research
• Early Environment
• Developmental Origins of Child Health
• Expired projects