Plasmodium knowlesi is a zoonotic parasite that causes malaria in humans. The pathogen has a natural host reservoir in certain macaque species and is transmitted to humans via mosquitoes of the Anopheles Leucosphyrus Group. The risk of human P. knowlesi infection varies across Southeast Asia and is dependent upon environmental factors.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

In-solution hybridisation enrichment of genetic variation is a valuable methodology in human paleogenomics. It allows enrichment of endogenous DNA by targeting genetic markers that are comparable between sequencing libraries. Many studies have used the 1240k reagent-which enriches 1,237,207 genome-wide SNPs-since 2015, though access was restricted. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

Tuberculosis (TB) is a major public health concern in low- and middle-income countries including Ethiopia. This study aimed to assess the spatiotemporal distribution of TB and identify TB risk factors in Ethiopia's Oromia region. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• September 2023

To examine and synthesise recent evidence on the role of grandparents in shaping children's dietary health. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• Jun 2023

Previous studies have reported an association between low birthweight and elevated blood pressure (BP) in adulthood, but few have examined the relationship between foetal growth and adult BP. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

While UV radiation is a skin carcinogen, this should not obscure the growing evidence that sunlight has significant health benefits, including impacts on cardiovascular and metabolic health. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Undernutrition is a major risk factor for tuberculosis (TB), which is estimated to be responsible for 1.9 million TB cases per year globally. The effectiveness of micronutrient supplementation on TB treatment outcomes and its prognostic markers (sputum conversion, serum zinc, retinol and haemoglobin levels) has been poorly understood. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

As malaria incidence decreases and more countries move towards elimination, maps of malaria risk in low-prevalence areas are increasingly needed. For low-burden areas, disaggregation regression models have been developed to estimate risk at high spatial resolution from routine surveillance reports aggregated by administrative unit polygons. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

For 20 years, the hygiene hypothesis has dominated attempts to explain the increasing prevalence of allergic disease. A causal link between maternal innate immu ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Human embryonic stem cell-derived neural stem cells (hESC-NSCs) are an attractive cell type for studying ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• April 2010