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        Research

        Immunological processes driving IgE sensitisation and disease development in males and females

        In this review, we discuss recent mechanistic studies casting further light on how the expression of sex hormones may influence the innate and adaptive immune system ...

        Research

        Dissecting the regulation of bile-induced biofilm formation in staphylococcus aureus

        Wall teichoic acid may be important for protecting S. aureus against exposure to bile ...

        Research

        Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

        UVB-induced p53-mediated cell cycle arrest and apoptosis are reduced in the presence of heat stress, leading to increased survival of DNA damaged cells ...

        Research

        Lack of replication for the myosin-18B association with mathematical ability in independent cohorts

        Twin studies indicate that dyscalculia (or mathematical disability) is caused partly by a genetic component, which is yet to be understood at the molecular... ...

        Research

        IgE and IgG binding patterns and T-cell recognition of fel d 1 and Non-Fel d 1 cat allergens

        To compare IgE and IgG antibody binding and T-cell recognition of the major cat allergen Fel d 1 with other cat proteins with known IgE binding properties. ...

        Research

        Nasopharyngeal carriage of Streptococcus pneumoniae: prevalence and risk factors in HIV-positive children in Tanzania

        Pneumococcal colonization of the nasopharynx is especially common in young children and is a pre-requisite for pneumococcal disease... ...

        Research

        The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

        The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways. ...

        Research

        Guidelines for pregnancy: What's an acceptable risk, and how is the evidence (finally) shaping up?

        This paper reviews the evidence from systematic reviews and meta-analyses examining the risk from low and moderate levels of prenatal alcohol exposure. ...

        Research

        The recruitment and retention of Speech and Language Therapists: What do university students find important?

        The increasing need for speech and language therapy (SLT) services, coupled with poor employment retention rates, poses serious cost-benefit considerations. ...

        Research

        The effectiveness of community friendship groups on participant social and mental health: a meta-analysis

        Social disconnectedness and isolation are risk factors for poor mental health. Community-based friendship group interventions have been designed to increase an individual's social capital and consequently their mental wellbeing. Structured and unstructured friendship groups reflect two distinct approaches to friendship group interventions. ...

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