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        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        Recent studies based on hospital admissions have reported a significant increase in anaphylaxis prevalence. ...

        Research

        Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease

        Chronic inflammation may expand sub-populations of T cells expressing CTLA-4 in COPD patients and therefore impair T-cell function ...

        Research

        The 2015 Middle Childhood Survey (MCS) of mental health and well-being at age 11 years in an Australian population cohort

        most children report mental health and well-being, but the population distribution spanned the full range of possible scores on every construct. ...

        Research

        The role of preschool quality in promoting child development: evidence from rural Indonesia

        This article examines the relationship between preschool quality and children’s early development in a sample of over 7900 children enrolled in 578 preschools in rural Indonesia. ...

        Research

        Genotype and phenotype spectrum of NRAS germline variants

        Here we describe 19 new cases with RASopathy due to disease-causing variants in NRAS ...

        Research

        Somatosensory discrimination intervention improves body position sense and motor performance in children with hemiplegic cerebral palsy

        The intervention group improved in goal performance, proprioception, and bimanual hand use and maintained improvement at 6-mo follow-up. ...

        Research

        Systematic chemical and molecular profiling of MLL-rearranged infant acute lymphoblastic leukemia reveals efficacy of romidepsin

        Present a valuable resource for drug discovery and have identified ROM as a promising therapeutic for MLL-rearranged iALL ...

        Research

        Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries

        These summary measures can also be used to quantify the component of variation in epidemiology that is related to sociodemographic development. ...

        Research

        Rheumatic heart disease in Indigenous children in northern Australia: Differences in prevalence and the challenges of screening

        This study compared regional differences in the prevalence of rheumatic heart disease in Indigenous Australian children, and describes the logistical and... ...

        Research

        DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium

        VEGFR-3 signaling plays a central role in lymphatic biology, both in the development of the lymphatic network during embryogenesis as well as in... ...

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