Staphylococcus aureus is a common cause of bacteremia, yet the epidemiology and predictors of poor outcome remain inadequately defined in childhood. ISAIAH (Invasive Staphylococcus aureus Infections and Hospitalizations in children) is a prospective, cross-sectional study of S. aureus bacteremia in children hospitalized in Australia and New Zealand over 24 months. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Acute poststreptococcal glomerulonephritis (APSGN) is an immune complex-induced glomerulonephritis that develops as a sequela of streptococcal infections. This article provides guidelines for the surveillance of APSGN due to group A Streptococcus (Strep A). The primary objectives of APSGN surveillance are to monitor trends in age- and sex-specific incidence, describe the demographic and clinical characteristics of patients with APSGN, document accompanying risk factors, then monitor trends in frequency of complications, illness duration, hospitalization rates, and mortality. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Described antimicrobial resistance mechanisms enable bacteria to avoid the direct effects of antibiotics and can be monitored by in vitro susceptibility testing and genetic methods. Here we describe a mechanism of sulfamethoxazole resistance that requires a host metabolite for activity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Impetigo is a highly contagious bacterial infection of the superficial layer of skin. Impetigo is caused by group A Streptococcus (Strep A) and Staphylococcus aureus, alone or in combination, with the former predominating in many tropical climates. Strep A impetigo occurs mainly in early childhood, and the burden varies worldwide. It is an acute, self-limited disease, but many children experience frequent recurrences that make it a chronic illness in some endemic settings. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Asha Cheryl John Jonathan Marianne Bowen Bridge Jacky Carapetis AM Mullane AC CB JJ JR MM BA MBBS DCH FRACP PhD GAICD AM MBBS FRACP FAFPHM PhD FAHMS ...

• 1. Telethon Kids Institute
• Projects
• See, Treat, Prevent Skin Sores and Scabies (SToP) Trial

Asha Cheryl John Jonathan Marianne Bowen Bridge Jacky Carapetis AM Mullane AC CB JJ JR MM BA MBBS DCH FRACP PhD GAICD AM MBBS FRACP FAFPHM PhD FAHMS ...

• 1. Telethon Kids Institute
• Projects
• See, Treat, Prevent Skin Sores and Scabies (SToP) Trial

Marianne John Rebecca Stephanie Asha Jonathan Mullane Jacky Pavlos Enkel Bowen Carapetis AM MM JJ RP SE AC JR BSc (OT) PhD, MSFS, BSc (Hons), MPH, ...

• 1. Telethon Kids Institute
• Projects

These data support that children are not just 'little adults' in the AMR era, and analyses by age group are important to detect differences in antibiotic susceptibility ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The objective of this study was to describe the occurrence of skin infection associated hospitalizations in children born in Western Australia (WA). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017