17β-Estradiol is important in maintaining bone structure, and regulation of its synthesis plays an important role in the development of postmenopausal... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• September 2011

What is type 1 diabetes? Type 1 diabetes is a chronic autoimmune disease that results from the immune system attacking the insulin-producing cells of ...

• Rio Tinto Children's Diabetes Centre
• About Us

West Australian families are being asked to play a vital role in a major new national study to unravel the causes of childhood leukaemia. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2003
• July

Surgical resection of cancer remains the frontline therapy for millions of patients annually, but post-operative recurrence is common, with a relapse rate of around 45% for non-small cell lung cancer. The tumour draining lymph nodes (dLN) are resected at the time of surgery for staging purposes, and this cannot be a null event for patient survival and future response to immune checkpoint blockade treatment. This project investigates cancer surgery, lymphadenectomy, onset of metastatic disease, and response to immunotherapy in a novel model that closely reflects the clinical setting. In a murine metastatic lung cancer model, primary subcutaneous tumours were resected with associated dLNs remaining intact, completely resected or partially resected. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Article title Young D, Nagarajan L, de Klerk N, Jacoby P, Ellaway C, Leonard H. Sleep problems in Rett syndrome. Brain and Development. 2007; 29(10): ...

• Rett syndrome and Related Disorders
• Our Research
• Research snapshots

Here we focus on the problem of prioritising variants with respect to the observed disease phenotype ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

Our data indicate epigenetic dysregulation in the early stages of signal transduction through the T cell receptor complex, and likely reflects pathways modified by gene-environment interactions in food allergy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

The relationship between early life episodes of otitis media and later behavioural development with adjustment for confounders. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• July 2018

Rearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

We examined the baseline profile of a panel of T-ALL cell lines to determine factors that contribute to GC resistance without prior drug selection. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2009
• June 2009