The association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated in an Australian population-based... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011

Claims have been made about the benefits of fish oil supplementation. However, our research, including studies in collaboration with colleagues from ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Neonatal Neurodevelopment, Gut Health and Nutrition

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Discover. Prevent. ...

• Wal-yan Respiratory Research Centre
• Projects
• AREST CF (Cystic Fibrosis)
• Publications

Telethon Kids Institute researchers set out on a worldwide search to find out all they could about Rett syndrome, establishing databases and creating awareness. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2016
• May

To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Researchers from Perth's Telethon Kids Institute have been part of an international study that has found that genetic factors contribute to the development of l ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2014
• September

Rearrangements of the Mixed Lineage Leukemia (MLL/KMT2A) gene are present in approximately 10% of acute leukemias and characteristically define disease with poor outcome. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

COVID-19 is complicated by acute lung injury, and death in some individuals. It is caused by SARS-CoV-2 that requires the ACE2 receptor and serine proteases to enter AEC. We determined what factors are associated with ACE2 expression particularly in patients with asthma and COPD. We obtained lower AEC from 145 people from two independent cohorts, aged 2-89 years, Newcastle (n = 115) and Perth (n = 30), Australia. The Newcastle cohort was enriched with people with asthma (n = 37) and COPD (n = 38). Gene expression for ACE2 and other genes potentially associated with SARS-CoV-2 cell entry was assessed by qPCR, and protein expression was confirmed with immunohistochemistry on endobronchial biopsies and cultured AEC. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Non-burning (low-dose) UVR suppresses the BAT 'whitening', steatotic and pro-diabetic effects of consuming a high-fat diet through skin release of nitric oxide ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Genetic factors in airway epithelial cells that are functionally associated with asthma pathogenesis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016