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        Research

        Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

        We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria. ...

        News & Events

        Pandemic healthcare disruptions contributed to 76,000 extra malaria deaths: report

        Disruptions of malaria case management caused by the COVID-19 pandemic likely contributed to an extra 76,000 malaria deaths in sub-Saharan Africa, according to analysis by Telethon Kids Institute and Curtin University. ...

        Research

        Cord blood Streptococcus pneumoniae-specific cellular immune responses predict early pneumococcal carriage in high-risk infants in Papua New Guinea

        We aimed to explore whether newborns in high-risk areas have pre-existing pneumococcal-specific cellular immune responses that effects early acquisition. ...

        Research

        From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

        Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients alike. Despite advancements in brain cancer research driven by a technological revolution, translating our understanding of glioblastoma pathogenesis into improved clinical outcomes remains a critical unmet need. ...

        Research

        Psychosocial wellbeing, parental concerns, and familial impact of children with developmental coordination disorder

        Developmental Coordination Disorder (DCD) is a neurodevelopmental condition impacting motor skill acquisition and competence. While previous studies have identified adverse psychosocial outcomes in DCD, they are limited by small or population-screened, community-based samples. ...

        Research

        Paternal Attachment in the First Five Years: the Role of Self-compassion, Negative Emotional Symptoms, Parenting Stress, and Parent Self-efficacy

        Father-child attachment during the first five years of life plays a vital role in child health and wellbeing but remains an under-researched area. Recently, self-compassion has emerged as a mechanism through which parent–child attachment may be optimized via its capacity to promote parental mental health and wellbeing, yet little is known about self-compassion among fathers specifically. ...

        Research

        Australian Psychologists Experiences with Digital Mental Health: a Qualitative Investigation

        Digital mental health is changing the landscape of service delivery by addressing challenges associated with traditional therapy. However, practitioners’ use of these resources remains underexamined. ...

        Research

        No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults

        The acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample ...

        Research

        Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

        A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages ...

        Research

        Barriers to Parent–Child Book Reading in Early Childhood

        Parent–child book reading interventions alone are unlikely to meet needs of children and families for whom the absence of reading is psychosocial risk factor ...

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