Diabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus, but whether stretches of differentially methylated regions can also be identified in adolescent GDM offspring is unknown. ...

• 1. Telethon Kids Institute
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• 2024
• May 2024

The discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences. ...

• 1. Telethon Kids Institute
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• 2022
• October 2022

Neurodevelopmental disorders (NDDs), such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder, and intellectual disability (ID), commonly emerge during early development and impact functioning across cognitive, social-emotional, communication, and sensorimotor domains. ...

• 1. Telethon Kids Institute
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• 2017
• March 2017

We now have a growing number of epigenetic alterations in disease, and this offers a chance to increase sensitivity and specificity of future diagnostics and therapies ...

• 1. Telethon Kids Institute
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• 2020
• April 2020

Childhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown. ...

• 1. Telethon Kids Institute
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• Reports and Findings
• 2012
• June 2012

The Wesfarmers Centre is pleased to announce the successful applications for the 2016 Round 2 Wesfarmers Centre Seed Funding. The Wesfarmers Centre ...

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Cerebral palsy (CP) is a lifelong physical disability, resulting from maldevelopment or damage to the developing brain. All children with CP have a disorder of movement and posture, but this is often accompanied by disorders of intellect, sensation, behaviour and epilepsy. Long-standing CP registers and surveillance systems estimate the prevalence of CP as approximately 2 per 1000 live births; however variations are seen over time and in different regions of the world. ...

• 1. Telethon Kids Institute
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• 2023
• February 2023

Understanding how and why these disorders co-occur has important implications for diagnosis, treatment, and prognosis, as well as for developing fundamental... ...

• 1. Telethon Kids Institute
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• 2015
• May 2015

Our results reveal the complexity of Leishmania donovani evolution in the Indian subcontinent in response to drug treatment ...

• 1. Telethon Kids Institute
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• 2016
• January 2016

In this study of hand shape analysis, we introduce the reader already familiar with the field of twin research to the potential utility of geometric... ...

• 1. Telethon Kids Institute
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• 2013
• April 2013