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        Research

        Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers

        The bacille Calmette-Guérin (BCG) vaccine has immunomodulatory "off-target" effects that have been hypothesized to protect against coronavirus disease 2019.  ...

        Research

        Effectiveness of Palivizumab against Respiratory Syncytial Virus: Cohort and Case Series Analysis

        Palivizumab appeared effective for reducing virologically confirmed respiratory syncytial virus in this high-risk cohort ...

        Research

        S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccine

        Based on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage ...

        Research

        B Part of It School Leaver protocol: an observational study to assess the impact of a meningococcal serogroup B vaccine programme on carriage of Neisseria meningitidis

        This study will assess the impact of MenB vaccine (4CMenB) on carriage prevalence in school leavers in South Australia ...

        Research

        Advances in Vaccines to Prevent Viral Respiratory Illnesses in Children

        Childhood vaccination has played a critical role in the reduction of morbidity and mortality from communicable diseases, including specific respiratory pathogens ...

        Research

        Record linkage study of the pathogen-specific burden of respiratory viruses in children

        Reliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses ...

        Research

        Identification of generic and pathogen-specific cord blood monocyte transcriptomes reveals a largely conserved response in preterm and term newborn infants

        These data provide novel insights into the functionality of neonatal monocytes at birth ...

        Research

        Transiently increased IgE responses in infants and pre-schoolers receiving only (DTaP) vaccines compared to those initially receiving at least one dose of DTwP vaccine

        Confirm the generalised IgE-trophic activity of the DTaP vaccine in pre-schoolers and demonstrate similar (albeit transient) effects in infants ...

        Research

        A longitudinal study of natural antibody development to pneumococcal surface protein A families 1 and 2 in Papua New Guinean Highland children: a cohort study

        Pneumococcal surface protein A is immunogenic and natural anti-PspA immune responses are acquired through exposure and develop with age ...

        Research

        Persistence of the immune responses and cross-neutralizing activity with Variants of Concern following two doses of adjuvanted SCB-2019 COVID-19 vaccine

        We have previously reported the safety and immunogenicity four weeks after two doses of the Clover COVID-19 vaccine candidate, SCB-2019, a stabilized pre-fusion form of the SARS-CoV-2 S-protein (S-trimer). We now report persistence of antibodies up to 6 months after vaccination, and cross-neutralization titers against three Variants of Concern. ...

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