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        Research

        Rationale and methods of a randomized controlled trial of immunogenicity, safety and impact on carriage of pneumococcal conjugate and polysaccharide vaccines in infants in Papua New Guinea

        Vaccination trials in high endemicity areas are needed to provide evidence and guidance on idea strategies to protect children in these areas against infections ...

        Research

        Taking a prebiotic approach to early immunomodulation for allergy prevention

        In this review we examine maternal and infant dietary sources of prebiotics with a particular focus on non-digestible oligosaccharides, which undergo SCFA. ...

        Research

        Effects of prenatal n-3 fatty acid supplementation on offspring resolvins at birth and 12 years of age: a double-blind, randomised controlled clinical trial

        This study aimed to assess the effect of n-3 fatty acid supplementation in pregnancy on offspring SPM at birth and 12 years of age (12 years) ...

        Research

        Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis

        The aim of our study was to characterize the activity of TNAP on TLR agonists and assess the concentrations of plasma ALP during late-onset sepsis in newborns. ...

        Research

        Blueprint for the House Dust Mite

        The completeness of the coverage of a genome assembly is a critical starting point for all genomic projects so considerable attention is given to the sequencing metrics, which showed high indicators of success. ...

        Research

        A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

        To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. ...

        Research

        The Risk of Neurodevelopmental Disabilities in Children of Immigrant and Refugee Parents: Current Knowledge and Directions for Future Research

        We investigated the literature from 2002 to 2016 describing the risk of ASD, intellectual disability and ADHD in children of refugee and immigrant backgrounds. ...

        Research

        Risk of Developmental Disorders in Children of Immigrant Mothers: A Population-Based Data Linkage Evaluation

        Increased risk of autism spectrum disorder with intellectual disability and cerebral palsy with intellectual disability for mothers of some foreign-born groups ...

        Research

        Fetal alcohol spectrum disorder and youth justice: a prevalence study among young people sentenced to detention in Western Australia

        This study of young people in detention in Western Australia, has documented a high prevalence of FASD and severe neurodevelopmental impairment ...

        Research

        Macrolides in children with community-acquired pneumonia: Panacea or placebo?

        Pneumonia, most often caused by a respiratory virus, is common in childhood. ...

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