The current study brought a bioecological approach to children’s early vocabulary development using data from the Longitudinal Study of Australian Children... ...

• 1. Telethon Kids Institute
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• 2011
• October 2011

Both children and adults benefit from living in communities and neighborhoods that are rich in social capital. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011

The Opportunity: Vaccine Trials Group are looking for a Research Nurse to work in our vibrant team. The Research Nurse will work alongside the ...

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Co-Head, Leukaemia Translational Research ...

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PTEN mutation occurs in a variety of aggressive cancers and is associated with poor patient outcomes. Recent studies have linked mutational loss of PTEN to reduced RAD51 expression and function, a key factor involved in the homologous recombination (HR) pathway. However, these studies remain controversial, as they fail to establish a definitive causal link to RAD51 expression that is PTEN-dependent, while other studies have not been able to recapitulate the relationship between the PTEN expression and the RAD51/HR function. ...

• 1. Telethon Kids Institute
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• 2020
• October 2020

COVID-19 has caused a global public health crisis affecting most countries, including Ethiopia, in various ways. This study maps the vulnerability to infection, case severity and likelihood of death from COVID-19 in Ethiopia. Thirty-eight potential indicators of vulnerability to COVID-19 infection, case severity and likelihood of death, identified based on a literature review and the availability of nationally representative data at a low geographic scale, were assembled from multiple sources for geospatial analysis. Geospatial analysis techniques were applied to produce maps showing the vulnerability to infection, case severity and likelihood of death in Ethiopia at a spatial resolution of 1 km×1 km. ...

• 1. Telethon Kids Institute
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• 2021
• February 2021

Soil transmitted helminth infections are estimated to impact 24% of the world's population and are responsible for chronic and debilitating morbidity. Disadvantaged communities are among the worst affected and are further marginalized as infection prevalence fuels the poverty cycle. ...

• 1. Telethon Kids Institute
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• 2024
• February 2024

Programmable DNA endonucleases derived from bacterial genetic defense systems, exemplified by CRISPR-Cas9, have made it significantly easier to perform genomic modifications in living cells. However, unprogrammed, off-target modifications can have serious consequences, as they often disrupt the function or regulation of non-targeted genes and compromise the safety of therapeutic gene editing applications.  ...

• 1. Telethon Kids Institute
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• 2024
• April 2024

Advancements in genomic profiling led to the discovery of four major molecular subgroups in medulloblastoma (MB), which have now been incorporated into the World Health Organization classification of central nervous system tumors. The current study aimed to determine the prognostic significance of the MB molecular subgroups among children in Malaysia.  ...

• 1. Telethon Kids Institute
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• 2023
• November 2023

Neutrophils are the most abundant immune cell in circulation. However, due to a number of technical challenges for researchers, including the neutrophil's short lifespan and difficulties with preservation, they are often discarded during blood processing and thus ignored in cohort studies. As such, the contribution of neutrophils to disease and their involvement in disease mechanisms is less explored compared with other immune cell types. ...

• 1. Telethon Kids Institute
• Our research
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• 2023
• February 2023