To show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• February 2012

Suggests that IL-1R1 expression provides an additional level of Myd88-dependent signaling during this period of heighted susceptibility to infection. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

This study examined whether maternal and/or fetal folate status in pregnancy is associated with infant allergic outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

The increasing use of assisted reproductive techniques and hormonal manipulation during pregnancy may have been associated with an apparent rise in the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

This paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• October 2015

The aim of this study was to investigate the relationship between a child's weight and a broad range of family and maternal factors. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2007
• June 2007

The Childhood Allergy and Immunology Research Team at the Telethon Kids Institute are currently conducting four studies, through The ORIGINS Project, investigating nutritional strategies in the diets of mothers and babies and how these may reduce the development of allergies. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2020
• June

Childhood is a critical period of immune development. During this time, naïve CD4 T cells undergo programmed cell differentiation, mediated by epigenetic changes, in response to external stimuli leading to a baseline homeostatic state that may determine lifelong disease risk. However, the ontogeny of epigenetic signatures associated with CD4 T cell activation during key developmental periods are yet to be described. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

In December 2016, a panel of experts was convened by the International Scientific Association for Probiotics an Prebiotics to review the scope of prebiotic. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• August 2017

We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017