The ability to balance conflicting functional demands is critical for ensuring organismal survival. The transcription and repair of the mitochondrial genome requires separate enzymatic activities that can sterically compete, suggesting a life-long trade-off between these two processes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity in terms of molecularly distinct entities, cellular origins and genetic drivers than anticipated from histological assessment. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

Here, we demonstrate that group A Streptococcus (GAS) utilises Mn(II) import via MtsABC during conditions of hydrogen peroxide stress ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• December 2015

Connective tissue growth factor (CTGF/CCN2) has been shown previously to be aberrantly expressed in a high proportion of paediatric precursor B cell acute... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

This paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• September 2015

Participation in population-based case-control studies: does the observed decline vary by socio-economic status? ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• October 2011

The association between parental smoking and risk of childhood acute lymphoblastic leukemia (ALL) was investigated ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012

We explored familial aggregation of cancer in a population-based case-control study using genealogical record linkage and designed to overcome limitations of... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

Discover. Prevent. Cure. Healthy Lungs & Immune Development Focusing on the developmental trajectories of respiratory health includes developing ...

• Wal-yan Respiratory Research Centre
• Our research
• Focus areas for the Centre