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        Research

        Towards a molecular characterization of autism spectrum disorders: An exome sequencing and systems approach

        This paper profiles the functional pattern of DNA variants found at a higher rate in patients with autism spectrum disorder (ASD), X-linked intellectual... ...

        Research

        Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergy

        Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. ...

        Research

        Waning vaccine immunity in teenagers primed with whole cell and acellular pertussis vaccine: Recent epidemiology

        The recent epidemics of pertussis (whooping cough) in parts of the USA and Australia have led to the largest numbers of annual cases reported in over half a... ...

        Research

        Assessment and management of hypoglycemia in children and adolescents with diabetes

        This paper provides clinical practice guidelines for treating low blood sugar in children and adolescents with Type 1 diabetes. ...

        Research

        Infection and Vaccines

        Listed are the Telethon Kids Institute research teams involved in our Infection and Vaccines Program. This program sits under the Early Environment research theme. ...

        Research

        Reidentification with Birth-Registered Sex in a Western Australian Pediatric Gender Clinic Cohort

        Some young people who identify as transgender and seek gender-affirming medical care subsequently reidentify with their sex registered at birth. Evidence regarding the frequency and characteristics of this experience is lacking.  ...

        Research

        The valence-specific empathy imbalance hypothesis of autism: The role of autistic traits, alexithymia, emotion dysregulation, and gender differences

        Individuals exhibiting pronounced autistic traits (e.g., social differences and specialised interests) may struggle with cognitive empathy (i.e., the ability to infer others' emotions), although the relationship with affective empathy (i.e., the ability to share others' emotions) is less clear in that higher levels of autistic traits may be linked with increased affective empathy for negative emotions but reduced affective empathy for positive emotions. The current study investigates this empathy profile and whether alexithymia and emotion dysregulation help to explain it. ...

        Research

        Determinants of drug-resistant tuberculosis in Hunan province, China: a case-control study

        Drug-resistant tuberculosis (DR-TB) is a major public health threat in Hunan Province, with an increasing clinical burden in recent years. This study aimed to identify socio-demographic and clinical factors associated with DR-TB in Hunan province, China. ...

        Research

        Mapping the incidence rate of typhoid fever in sub-Saharan Africa

        With more than 1.2 million illnesses and 29,000 deaths in sub-Saharan Africa in 2017, typhoid fever continues to be a major public health problem. Effective control of the disease would benefit from an understanding of the subnational geospatial distribution of the disease incidence. ...

        Research

        Supportive care needs and associated factors among caregivers of patients with colorectal cancer: a cross-sectional study

        To assess the level of supportive care needs of caregivers of colorectal cancer patients and explore the related key influencing factors. Totaling 283 caregivers of patients with colorectal cancer were investigated in this study.  ...

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