This paper reports on a five-year project to measure student wellbeing across an education system using the Middle Years Development Instrument ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

The algorithm that was tested against moderate exercise and an overreading glucose sensor performed well in terms of hypoglycemia avoidance ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

This paper examined the link between UV exposure and vitamin D production in young children to determine how long it takes for sun exposure to affect serum... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

The outcome for children with high-grade gliomas (HGG) remains dismal, with a 2-year survival rate of only 10% to 30%. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• October 2013

Embrace @ Telethon Kids Institute researcher Dr Alix Woolard at The Y's Inside Our Minds launch ...

• Embrace @ Telethon Kids
• News and events
• 2023

In addition to its role in blocking TH2 effector activation in the late-phase allergic response, IL-10 is a known IgG1 switch factor ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic anti-cancer effects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Parental assistance with children's emotion regulation (ER) is a form of emotion socialization behavior that has recently been operationalized with the development of the Parent Assistance with Child Emotion Regulation (PACER) questionnaire. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

We review findings from our previous studies which show the application of a person-based resilience framework of analysis in the context of WA aboriginal youth ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018