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        Research

        Vulnerable from the first breath - epithelial dysfunction and respiratory outcomes in children

        Anthony David Stephen Susan Kicic Martino Stick Prescott A DM SM SL BSc (Hons) PhD BSc PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Rothwell ...

        News & Events

        Telethon Kids Institute researcher wins Premier’s Science Award

        Infectious diseases researcher, Dr Asha Bowen, has won the Early Career Scientist of the Year Premier's Science Award for 2017. ...

        Research

        Late-talking and risk for behavioral and emotional problems during childhood and adolescence

        Although many toddlers with expressive vocabulary delay ("late talkers") present with age-appropriate language skills by the time they are of school age,... ...

        Research

        Energy drink consumption among young Australian adults: Associations with alcohol and illicit drug use

        Australian energy drink users tend to have heavier alcohol consumption patterns be a cigarette smoker and use illicit drugs relative to non-users. ...

        Research

        Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis

        We hypothesized that the presence of these markers of cystic fibrosis lung disease in the first 2 years of life would be associated with reduced lung... ...

        Research

        The Changing Detection Rate of Respiratory Syncytial Virus in Adults in Western Australia between 2017 and 2023

        The incidence of respiratory syncytial virus (RSV) in adults is inadequately defined and the impact of SARS-CoV-2-related non-pharmaceutical interventions (NPIs) is underexplored. Using laboratory data, we described the detection rate of RSV in adults ≥16 years in Western Australia (WA) between 2017 and 2023. ...

        Research

        Developing a prediction model to estimate the true burden of respiratory syncytial virus (RSV) in hospitalised children in Western Australia

        Respiratory syncytial virus (RSV) is a leading cause of childhood morbidity, however there is no systematic testing in children hospitalised with respiratory symptoms. Therefore, current RSV incidence likely underestimates the true burden. ...

        Research

        A Meta-analysis on the Role of Children in Severe Acute Respiratory Syndrome Coronavirus 2 in Household Transmission Clusters

        The role of children in the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains highly controversial. To address this issue, we performed a meta-analysis of the published literature on household SARS-CoV-2 transmission clusters (n = 213 from 12 countries). Only 8 (3.8%) transmission clusters were identified as having a pediatric index case. ...

        Research

        Excess respiratory mortality and hospitalizations associated with influenza in Australia, 2007-2015

        Influenza is the most common vaccine-preventable disease in Australia, causing significant morbidity and mortality. We assessed the burden of influenza across all ages in terms of influenza-associated mortality and hospitalizations using national mortality, hospital-discharge and influenza surveillance data. ...

        News & Events

        Telethon Kids Institute activities at Telethon 2018

        As one of Telethon’s earliest and most long-standing beneficiaries, we are incredibly proud to be taking part in the Telethon Weekend again in 2018. ...

        Research

        ARIEL study

        Anthony David Stephen Susan Kicic Martino Stick Prescott A DM SM SL BSc (Hons) PhD BSc PhD MB BChir PhD MRCP FRACP MBBS BMedSci PhD FRACP Rothwell ...

        Research

        Maternal Late-Pregnancy Serum Unmetabolized Folic Acid Concentrations Are Not Associated with Infant Allergic Disease: A Prospective Cohort Study

        The increase in childhood allergic disease in recent decades has coincided with increased folic acid intakes during pregnancy. Circulating unmetabolized folic acid (UMFA) has been proposed as a biomarker of excessive folic acid intake. We aimed to determine if late-pregnancy serum UMFA and total folate concentrations were associated with allergic disease risk in the offspring at 1 y of age in a population at high risk of allergy. ...

        Research

        Impact of Micronutrient Status during Pregnancy on Early Nutrition Programming

        Globally and even in high-income countries where a balanced diet is generally accessible, an inadequate maternal micronutrient status is common ...

        Research

        Prebiotics: mechanisms and preventive effects in allergy

        In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention ...

        Research

        Increased Use of Adrenaline in the Management of Childhood Anaphylaxis Over the Last Decade

        There was a significant improvement in the management of anaphylaxis after the introduction of intensified physician training programs ...

        Research

        Clinical Ecology-Transforming 21st-Century Medicine with Planetary Health in Mind

        The grand, interconnected challenges of our time demands that all of medicine be viewed from an ecological perspective ...

        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        We conducted an investigation of all cases coded as anaphylaxis presenting to the main tertiary PED in Perth, Australia, where all coding is performed by staff. ...

        Research

        An Australian Consensus on Infant Feeding Guidelines to Prevent Food Allergy: Outcomes From the Australian Infant Feeding Summit

        Infant feeding in the first postnatal year of life has an important role in an infant's risk of developing food allergy ...

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