There is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

Dengue fever in Sumatra and Kalimantan was highly seasonal and associated with climate factors and deforestation ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

Substantial progress has been made in reducing the burden of malaria in Africa since 2000, but those gains could be jeopardised if the COVID-19 pandemic affects the availability of key malaria control interventions. The aim of this study was to evaluate plausible effects on malaria incidence and mortality under different levels of disruption to malaria control. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Households are known to be high-risk locations for the transmission of communicable diseases. Numerous modelling studies have demonstrated the important role of households in sustaining both communicable diseases outbreaks and endemic transmission, and as the focus for control efforts. However, these studies typically assume that households are associated with a single dwelling and have static membership. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Group A streptococcal (GAS) pharyngitis has traditionally been considered the sole precursor of acute rheumatic fever (ARF). Evidence from Australia, however, suggests that GAS skin infections may contribute to the pathogenesis of ARF. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Implementation of lifelong ART of all HIV-infected women has the potential to improve maternal determinants of protective immunity in the young infant ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

This study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji. We used data from four annual cross-sectional surveys, pre- and post-introduction of ten-valent pneumococcal conjugate vaccine in October 2012. Infants, toddlers, children, and their caregivers participated. Pneumococci were detected and quantified using lytA qPCR, with molecular serotyping by microarray. Logistic and quantile regression were used to determine predictors of pneumococcal carriage and density, respectively. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

Protection may be further improved by integrating these approaches, namely vaccinating the neonate under the cover of vertically transferred maternal immunity ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

The prevalence of group A streptococcal disease remains high among symptomatic individuals residing in Africa ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Recent vaccine mandates in Australia, as in other high income settings, have sought to change the behavior of parents, including those who would otherwise access nonmedical exemptions. Since 2014, Australian state governments have introduced and progressively tightened policies restricting the access of unvaccinated children to early education and child care. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020