Protracted bacterial bronchitis (PBB) is a leading cause of chronic wet cough in children. The current standard treatment in European and American guidelines is 2 weeks of antibiotics, but the optimal duration of therapy is unknown. We describe the first randomised controlled trial to assess the duration of antibiotic treatment in children with chronic wet cough and suspected PBB. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Although preterm birth is associated with later deficits in lung function, there is a paucity of information on geographical differences and whether improvements occur over time, especially after surfactant was introduced. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

This paper examines whether adolescents can be reliably categorized into subgroups based on their patterns of anxiety levels over time and whether low levels of social support from parents, peers, and their school, and high levels of peer victimization, predict a pattern of increasing anxiety. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Establishing the underlying cause in a child with chronic suppurative lung disease (CSLD) allows for targeted treatment and screening for associated complications. One cause of CSLD is primary ciliary dyskinesia (PCD). Testing for PCD requires specialist expertise which is not widely available. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

BRAF genomic alterations are the most common oncogenic drivers in pediatric low-grade glioma. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• November 2023

Research has shown differences in how fathers and mothers respond to a child's cancer diagnosis. Previous studies have highlighted that sociocultural norm shape fathers' experiences of their child's cancer diagnosis. Our phenomenological qualitative study aimed to examine the lived experiences of fathers whose children have been diagnosed with cancer and explore the impact of sociocultural gender roles. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

ZFTA-RELA (formerly known as c11orf-RELA) fused supratentorial ependymoma has been recognized as a novel entity in the 2016 WHO classification of CNS tumors and further defined in the recent 2021 edition. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

RNA-binding proteins and mitochondrial ribosomes have been found to be linchpins of mitochondrial gene expression in health and disease. The expanding repertoire of proteins that bind and regulate the mitochondrial transcriptome has necessitated the development of new tools and methods to examine their molecular functions. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Survival statistics, estimated using data from national cystic fibrosis (CF) registries, inform the CF community and monitor disease progression. This study aimed to estimate survival among people with CF in Australia and to identify factors associated with survival. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

In this chapter, we describe the life course approach and explain key concepts and principles. We also review variations in life course theory across disciplines including differences in terminology and understanding of core elements of life course theory. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022