Climate change models predict that atmospheric carbon dioxide [CO2] levels will be between 700 and 900 ppm within the next 80yrs. In this study we aimed to assess the respiratory structure and function effects of long-term exposure to 890ppm CO2 from preconception to adulthood using a mouse model. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate ...

• 1. Telethon Kids Institute
• Projects

There are a multitude of ways that, with respect to early-life exposures and health, electronic nicotine delivery systems are a cause for concern ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

This review focuses on smokers and nonsmokers and evaluates the most recent data regarding the potential health effects of e-cigarettes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Males are generally more susceptible to respiratory infections; however, there are few data on the physiological responses to such infections in males and... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• March 2011

The aim of this study was to assess whether in utero tobacco smoke exposure alone affects early-life lung growth and development. Pregnant BALB/c mice... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

We propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

The rat model demonstrates that intrauterine growth restriction leads to a more heterogeneous distribution of airway lumen calibre in adulthood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• October 2017

Prenatal alcohol exposure is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022