The importance of lung recruitment before surfactant administration has been shown in animal studies. Well designed trials in preterm infants are absent. We aimed to examine whether the application of a recruitment manoeuvre just before surfactant administration, followed by rapid extubation (intubate-recruit-surfactant-extubate [IN-REC-SUR-E]), decreased the need for mechanical ventilation during the first 72 h of life compared with no recruitment manoeuvre (ie, intubate-surfactant-extubate [IN-SUR-E]). ...

• Telethon Kids Institute
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• 2021
• February 2021

Gene transfer to a donor cornea ex vivo can modulate corneal graft failure in experimental animal models. We compared a lentiviral vector (LV) carrying... ...

• Telethon Kids Institute
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• 2010
• May 2010

We are a collaborative group focused on the goal of improving outcomes for children with leukaemia. The Research Assistant will work in a research ...

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Honorary Research Associate ...

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Aneuploidies, and in particular, trisomies represent the most common genetic aberrations observed in human genetics today. To explore the presence of trisomies in historic and prehistoric populations we screen nearly 10,000 ancient human individuals for the presence of three copies of any of the target autosomes. We find clear genetic evidence for six cases of trisomy 21 (Down syndrome) and one case of trisomy 18 (Edwards syndrome), and all cases are present in infant or perinatal burials. ...

• Telethon Kids Institute
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• 2024
• February 2024

We demonstrate the feasibility of a plant breeding approach without compromising animal productivity to mitigate enteric methane emissions, which is one of the most significant challenges to global livestock production. ...

• Telethon Kids Institute
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• 2017
• September 2017

The group 7 allergens are important allergenic specificities for mite-sensitive patients and may need to be incorporated into new diagnostic and therapeutic... ...

• Telethon Kids Institute
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• 2011
• February 2011

The proteins examined were the homologues of the P4, P6, P26, and D15 proteins of Haemophilus influenzae. ...

• Telethon Kids Institute
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• 2013
• June 2013

We are looking for an experienced informatics specialist to help underpin the bioinformatics platform of the Telethon Kids Institute. This role will ...

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HDM allergy is associated with asthma, allergic rhinitis and atopic dermatitis. ...

• Telethon Kids Institute
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• 2012
• August 2012