Medulloblastoma is the most common malignant childhood brain tumor, and 5-year overall survival rates are as low as 40% depending on molecular subtype, with new therapies critically important. As radiotherapy and chemotherapy act through the induction of DNA damage, the sensitization of cancer cells through the inhibition of DNA damage repair pathways is a potential therapeutic strategy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

We strive for a future where no child will die from brain cancer because we have developed new therapies that will cure their disease. ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Cancer Program

Despite initial improvements in survival of infants with ALL since establishment of the first pediatric cooperative group ALL trials, the poor outcome has... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

This chapter summarizes recent advances in diffuse intrinsic pontine glioma and potential novel therapies ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

In this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

Sébastien Rishi Sury Laurence Timo Malinge Kotecha Cheung Lassmann SM RS LC T PhD MB ChB (Hons) MRCPCH FRACP PhD BPharm (Hons) MBA PhD BSc (Hons) MSc ...

• 1. Telethon Kids Institute
• Projects

Omar Merridee Sébastien Laurence Rishi Sury Terrance Timo Raelene W. Joost Elaskalani Wouters Malinge Cheung Kotecha Johns Lassmann Endersby ...

• 1. Telethon Kids Institute
• Projects

Emma de Jong EdJ Senior Research Officer emma.dejong@telethonkids.org.au Dr Emma de Jong obtained her PhD in 2016 from Murdoch University and is now ...

• 1. Telethon Kids Institute
• Contact us
• Our people
• Staff Profiles - D

Senior Research Officer ...

• 1. Telethon Kids Institute
• Contact us
• Our people
• Staff Profiles - F