Cells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly, which affects hiPS cell function. These differences include epigenetic memory and aberrations that emerge during reprogramming, for which the mechanisms remain unknown. ...

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• 2023
• August 2023

Consumer Representative Spotlight - Lisa Goldsworthy ...

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Tom Snelling T BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@telethonkids.org.au Head, ...

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Tom Snelling T BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@telethonkids.org.au Head, ...

• 1. Telethon Kids Institute
• Projects

Rheumatic heart disease (RHD) is a large, preventable, global public health burden. In New Zealand (NZ), acute rheumatic fever (ARF) and RHD rates are highest for Māori and Pacific children. This structured review explores the evidence for primary prevention interventions to diagnose and effectively treat group A Streptococcus (GAS) pharyngitis and skin infections to reduce rates of ARF and RHD. ...

• 1. Telethon Kids Institute
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• 2021
• April 2021

The results suggest that though the risk for RSV in the NICU remains low, personnel clothing are contaminated with RSV-RNA and may have a role in transmission ...

• 1. Telethon Kids Institute
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• 2016
• January 2016

Location: Bunbury, WA The Child Health, Development and Education has an opening for a casual Research Assistant position located in Bunbury, Western ...

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The Opportunity The Brain Tumour Research Program and Oncogenic Signalling Laboratory are collaborative groups composed of clinical and lab-based ...

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The Opportunity The Wesfarmers Centre of Vaccines & Infectious Diseases brings together a number of independent researchers and teams with a common ...

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COVID-19 has caused a global public health crisis affecting most countries, including Ethiopia, in various ways. This study maps the vulnerability to infection, case severity and likelihood of death from COVID-19 in Ethiopia. Thirty-eight potential indicators of vulnerability to COVID-19 infection, case severity and likelihood of death, identified based on a literature review and the availability of nationally representative data at a low geographic scale, were assembled from multiple sources for geospatial analysis. Geospatial analysis techniques were applied to produce maps showing the vulnerability to infection, case severity and likelihood of death in Ethiopia at a spatial resolution of 1 km×1 km. ...

• 1. Telethon Kids Institute
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• 2021
• February 2021