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        Research

        Early detection of lung function abnormalities in young children with cystic fibrosis

        In this review, we have examined the role of lung function testing in infants and preschool children with CF. ...

        Research

        Airway Epithelial Cells Condition Dendritic Cells to Express Multiple Immune Surveillance Genes

        AEC-conditioned DC showed selective upregulation of chemokines that recruit Th1 cells, but minimal change in chemokines linked to Th2 cell recruitment. ...

        Research

        MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63

        We hypothesized that reactivation of p53 by inhibition of its negative regulator will result in p53-mediated growth arrest and apoptosis. ...

        Research

        Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adults enrolled in a randomised controlled vaccine trial

        Viral respiratory infections are associated with significant morbidity and mortality. ...

        Research

        Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 children

        The aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC. ...

        Research

        Effectiveness of clindamycin and intravenous immunoglobulin, and risk of disease in contacts, in invasive group a streptococcal infections

        This paper reports on treatment, and preventing infection in close contact, of invasive group A streptococcal (iGAS) using the antibiotic clindamycin and... ...

        Research

        Examining ERBB2 as a candidate gene for susceptibility to leprosy (Hansen's disease) in Brazil

        This study examines whether polymorphisms in the ERBB2 gene were associated with leprosy in primary and replication cohorts from northeastern Brazil. ...

        Research

        Diverging Trends in Gastroenteritis Hospitalizations during Two Decades in Western Australian Aboriginal and Non-Aboriginal Children

        Our findings highlight the need to consider age, ethnicity, seasonality and climate when evaluating rotavirus vaccine programs. ...

        Research

        Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territory

        We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996. ...

        Research

        Dendritic cells and multiple sclerosis: Disease, tolerance and therapy

        Multiple sclerosis (MS) is a devastating neurological disease that predominantly affects young adults resulting in severe personal and economic impact. ...

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