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        411-420 of 654 results for 'Gene'

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        Research

        Representativeness of child controls recruited by random digit dialling

        Recruiting control subjects who are representative of the population from which the cases are drawn is a challenge in case-control studies ...

        Research

        Comparative drug screening in NUT midline carcinoma

        The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed. ...

        Research

        An atlas of human long non-coding RNAs with accurate 5′ ends

        Combining these findings with conservation data, we identify 19,175 potentially functional lncRNAs in the human genome. ...

        Research

        Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)

        Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies. ...

        Mitochondrial Medicine and Biology

        Mitochondrial diseases are devastating disorders for which there are no cures or effective treatments. Our project will focus on the prevention of mitochondrial diseases and discovery of effective cures. ...

        Research

        Cyclin-Dependent Kinase-Like 5 Deficiency Disorder: Clinical Review

        Clinical presentations and genetic variations in Cyclin-dependent kinase-like 5 deficiency disorder based on a systematic literature review and experience ...

        Research

        Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

        We investigated the relationship between the sensitivity of hundreds of cell lines to hundreds of drugs, and the relative expression levels of the targets ...

        Research

        Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia

        The aim of our study was to investigate whether CBL0137 has potential as a therapeutic and chemopotentiating compound in MLL-r leukemia ...

        Research

        Linking FANTOM5 CAGE peaks to annotations with CAGEscan

        Here, we present the production and quality control of CAGEscan libraries from 56 FANTOM5 RNA sources ...

        Research

        Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

        Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells ...

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