A landmark study has revealed an increase in the prevalence of mental health related issues among mothers of Aboriginal children in Western Australia. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2019
• July

Higher urinary albumin excretion, even within the normal range, is associated with early atherosclerosis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Severity and disease progression in people with Cystic Fibrosis is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides. CFTR exon 9 is an in-frame exon and hence the exclusion of this exon would excise only 31 amino acids but not alter the reading frame of the remaining mRNA. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Aspergillus is increasingly associated with lung inflammation and mucus plugging in early cystic fibrosis disease during which conidia burden is low and strains appear to be highly diverse. It is unknown whether clinical Aspergillus strains vary in their capacity to induce epithelial inflammation and mucus production. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Antimicrobial resistance poses a significant threat to modern healthcare as it limits treatment options for bacterial infections, particularly impacting those with chronic conditions such as cystic fibrosis (CF). Viscous mucus accumulation in the lungs of individuals genetically predisposed to CF leads to recurrent bacterial infections, necessitating prolonged antimicrobial chemotherapy. Pseudomonas aeruginosa infections are the predominant driver of CF lung disease, and airway isolates are frequently resistant to multiple antimicrobials. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

School toilets have been identified by sexuality and gender diverse (SGD) students as the least safe spaces in educational institutions. They are sites of verbal, physical and sexual victimisation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

We report an overall good adherence to ACE inhibitors and statins during a clinical trial, although there was a clear decline in adherence over time ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

We explored trends in six developed countries in three types of indicators of child maltreatment for children younger than 11 years,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• December 2011

Urban population growth in Nigeria may exceed the availability of affordable housing and basic services, resulting in living conditions conducive to vector breeding and heterogeneous malaria transmission. Understanding the link between community-level factors and urban malaria transmission informs targeted interventions. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may expedite the development of novel targeted treatment strategies. In this study, we performed transcriptomics on the airway and parenchyma using a house dust mite (HDM)-induced model of experimental asthma that replicates key features of the human disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023