Nick Gottardo NG MBChB FRACP PhD Co-Head, Brain Tumour Research nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour Research Professor Nick ...

• Telethon Kids Institute
• Projects

We report a term male with congenital acute erythroleukemia who achieved sustained remission with low-dose cytosine arabinoside alone ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

While chemotherapy remains the first-line treatment for many cancers, it is still unclear what distinguishes responders from non-responders. Here, we characterize the chemotherapy-responsive tumor microenvironment in mice, using RNA sequencing on tumors before and after cyclophosphamide, and compare the gene expression profiles of responders with progressors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Medulloblastoma is a highly malignant small round blue cell tumor of the posterior fossa ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Cardio-oncology is a new multidisciplinary area of expertise that seeks to pre-emptively and proactively address cardiac complications that emerge during and following cancer therapy. Modern therapies including molecular targeted therapy and immunotherapy have broadened the agents that can cause cardiac sequelae, often with complications arising within days to weeks of therapy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• December 2022

Central nervous system germinomas are treatment-sensitive tumors with excellent survival outcomes. Current treatment strategies combine chemotherapy with radiotherapy (RT) in order to reduce the field and dose of RT. Germinomas originating in the basal ganglia/thalamus have proven challenging to treat given their rarity and poorly defined imaging characteristics. Craniospinal, whole brain, whole ventricle, and focal RT have all been utilized; however, the best treatment strategy remains unclear. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Functional role of CTGF in altering disease progression in a lymphoid malignancy ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

Brain tumors presenting in infancy, especially during the first 6 months of life. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• September 2012

This study investigates the different patterns of relapse in patients with central nervous system mixed malignant germ cell tumors - treated with chemotherapy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

This study investigated the relapse and outcome patterns of patients with central nervous system mixed malignant germ cell tumors treated with chemotherapy-only ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015