Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Here, we present the production and quality control of CAGEscan libraries from 56 FANTOM5 RNA sources ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• October 2017

Restricted and repetitive behaviours constitute a core symptom domain of autism spectrum disorder ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• June 2016

In this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• November 2015

Our data support a highly generalizable model in which enhancer transcription is the earliest event in successive waves of transcriptional change during... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

The FANTOM5 project investigates transcription initiation activities in more than 1,000 human and mouse primary cells, cell lines and tissues using CAGE. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

In WA, 60,000 kids live with a rare disease, and of those about half do not have a diagnosis. At Telethon Kids, researchers are leading the charge in developing a method to identify genetic variations, so that kids like Charlotte can get answers. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2020
• October

Previous studies suggest that exposure to pesticides increases the risk of childhood acute lymphoblastic leukemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• October 2011

In view of its side effect profile, ketogenic diet (KD) administration should be supervised by a pediatric neurologist and specialist dietician. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• August 2017

Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children during acute virus-associated exacerbations and later during convalescence. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023