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        Research

        Aminoglycoside use in paediatric febrile neutropenia - Outcomes from a nationwide prospective cohort study

        Aminoglycosides are commonly prescribed to children with febrile neutropenia (FN) but their impact on clinical outcomes is uncertain and extent of guideline compliance is unknown. We aimed to review aminoglycoside prescription and additional antibiotic prescribing, guideline compliance and outcomes for children with FN. ...

        Research

        Variants associated with HHIP expression have sex-differential effects on lung function

        Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. ...

        Research

        Role of maternal mental health disorders on stillbirth and infant mortality risk: a protocol for a systematic review and meta-analysis

        We plan to examine whether prenatal maternal mental health disorders impact the risk of stillbirth and infant mortality ...

        Research

        Association between diesel engine exhaust exposure and lung function in Australian gold miners

        Diesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift ...

        Research

        The Evolving Landscape of e-Cigarettes: A Systematic Review of Recent Evidence

        This review focuses on smokers and nonsmokers and evaluates the most recent data regarding the potential health effects of e-cigarettes ...

        Research

        Microbiome and Functional Analysis of a Traditional Food Process: Isolation of a Novel Species (Vibrio hibernica) With Industrial Potential

        Vibrio hibernica is capable of metabolizing a unique carbohydrate profile at low temperatures ...

        Research

        Prevalence of group A Streptococcal infection in Africa to inform GAS vaccines for rheumatic heart disease: A systematic review and meta-analysis

        The prevalence of group A streptococcal disease remains high among symptomatic individuals residing in Africa ...

        Research

        ApoB48-remnant lipoproteins are associated with increased cardiometabolic risk in adolescents

        Plasma apoB48 remnant lipoproteins associate with cardiometabolic risk factors in adolescents and provide support for the screening of remnant cholesterol in youth ...

        Research

        Factors associated with pneumococcal carriage in children and adults in Fiji, using four cross-sectional surveys

        This study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji. We used data from four annual cross-sectional surveys, pre- and post-introduction of ten-valent pneumococcal conjugate vaccine in October 2012. Infants, toddlers, children, and their caregivers participated. Pneumococci were detected and quantified using lytA qPCR, with molecular serotyping by microarray. Logistic and quantile regression were used to determine predictors of pneumococcal carriage and density, respectively. ...

        Research

        Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomised controlled trial of PCV in Papua New Guinean infants

        Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting ...

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