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        Research

        A blueprint for a multi-disease, multi-domain Bayesian adaptive platform trial incorporating adult and paediatric subgroups: the Staphylococcus aureus Network Adaptive Platform trial

        The Staphylococcus aureus Network Adaptive Platform (SNAP) trial is a multifactorial Bayesian adaptive platform trial that aims to improve the way that S. aureus bloodstream infection, a globally common and severe infectious disease, is treated. In a world first, the SNAP trial will simultaneously investigate the effects of multiple intervention modalities within multiple groups of participants with different forms of S. aureus bloodstream infection. ...

        Research

        Infant Whole-Cell Versus Acellular Pertussis Vaccination in 1997 to 1999 and Risk of Childhood Hospitalization for Food-Induced Anaphylaxis: Linked Administrative Databases Cohort Study

        Evidence suggests that children who had received an initial priming dose of whole-cell pertussis (wP) vaccine, rather than acellular pertussis (aP) vaccine, had a lower risk of developing IgE-mediated food allergy, the most common cause of anaphylaxis-related hospital presentations of childhood. ...

        Research

        Progesterone receptor mediates ovulatory transcription through RUNX transcription factor interactions and chromatin remodelling

        Progesterone receptor (PGR) plays diverse roles in reproductive tissues and thus coordinates mammalian fertility. In the ovary, rapid acute induction of PGR is the key determinant of ovulation through transcriptional control of a unique set of genes that culminates in follicle rupture. However, the molecular mechanisms for this specialized PGR function in ovulation is poorly understood. ...

        Research

        Short-course, high-dose primaquine regimens for the treatment of liver-stage vivax malaria in children

        To assess the pharmacokinetics, safety, and tolerability of two high-dose, short-course primaquine (PQ) regimens compared with standard care in children with Plasmodium vivax infections. ...

        Research

        The Impact of the No Jab No Play and No Jab No Pay Legislation in Australia: A Scoping Review

        Australia has a long history of population-based immunisation programs including legislations. This paper reports on a review of evaluations of the impact of the federal No Jab No Pay (NJNPay) and state implemented No Jab No Play (NJNPlay) legislations on childhood immunisation coverage and related parental attitudes. ...

        Research

        Cumulative incidence of child protection system contacts among a cohort of Western Australian Aboriginal children born 2000 to 2013

        Reducing the over-representation of Aboriginal children in the child protection system is a key target for the Australian government. We aimed to provide more recent evidence on the population-level cumulative incidence of contacts for Aboriginal children with child protective services in Western Australia. ...

        Research

        Arcuate fasciculus and pre-reading language development in children with prenatal alcohol exposure

        Prenatal alcohol exposure (PAE) contributes to widespread neurodevelopmental challenges, including reading, and has been associated with altered white matter. Here, we aimed to investigate whether arcuate fasciculus development is associated with pre-reading language skills in young children with PAE. ...

        Research

        Psychometric Properties of the Polish Version of the Perth Emotional Reactivity Scale

        The Perth Emotional Reactivity Scale (PERS) is a 30-item self-report questionnaire that assesses the ease of activation, intensity, and duration of negative and positive emotions. Our study aimed to introduce and validate the Polish version of the PERS. ...

        Research

        Defining research priorities and needs in cancer symptoms for adults diagnosed with cancer: an Australian/New Zealand modified Delphi study

        This study asked consumers (patients, carers) and healthcare professionals (HCPs) to identify the most important symptoms for adults with cancer and potential treatment interventions. ...

        Research

        Special Issue on the Challenges for family and child well‐being in the new era

        Citation: Li J, Rönkä A, Han WJ. Special Issue on the Challenges for family and child well‐being in the new era. International Journal of Social ...

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