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        Research

        Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

        Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells. ...

        Research

        Feasibility of parental collected nasal swabs for virus detection in young children with cystic fibrosis

        No evidence to demonstrate relationships with symptoms and viruses, prolonged symptoms, prolonged shedding or patterns of virus infections in CF ...

        Research

        Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

        Epidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls. ...

        Research

        Piloting a self-compassion program to promote physical and psychological wellbeing in youth with T1D

        Amy Keely Liz Megan Asha Finlay-Jones Bebbington Davis Ansell Parkinson AFJ KB EA MA AP BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) ...

        Research

        Maternal prebiotic supplementation during pregnancy and lactation modifies the microbiome and short chain fatty acid profile of both mother and infant

        Improving maternal gut health in pregnancy and lactation is a potential strategy to improve immune and metabolic health in offspring and curtail the rising rates of inflammatory diseases linked to alterations in gut microbiota. Here, we investigate the effects of a maternal prebiotic supplement (galacto-oligosaccharides and fructo-oligosaccharides), ingested daily from <21 weeks' gestation to six months' post-partum, in a double-blinded, randomised placebo-controlled trial.  ...

        Research

        Knowledge, attitudes and practices related to the transition of emerging adults with type 1 diabetes from paediatric to adult care in Western Australia

        Keely Leanne Amy Bebbington Fried Finlay-Jones KB LF AFJ MClinPsych/PhD BSc DipEd MSpEd EdD BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin ...

        News & Events

        Community is tackling FAS in the Fitzroy Valley

        Among the highest rates of Fetal Alcohol Syndrome (FAS) worldwide have been reported by Aboriginal community leaders in the remote Fitzroy Valley. ...

        News & Events

        Early diagnosis for kids with autism

        Focussing attention on a child’s first year of life is proving to be a major breakthrough in autism research. ...

        News & Events

        National focus on Fetal Alcohol Spectrum Disorders welcomed

        Leading researchers into the effects of alcohol in pregnancy have thrown their support behind the recommendations of a national Inquiry into FASD. ...

        Research

        Child maltreatment: variation in trends and policies in six developed countries

        We explored trends in six developed countries in three types of indicators of child maltreatment for children younger than 11 years,... ...

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