BAL Inflammatory Markers Can Predict Pulmonary Exacerbations in Children With Cystic Fibrosis Discover. Prevent. Cure.   Background: Pulmonary ...

• Wal-yan Respiratory Research Centre
• Projects
• AREST CF (Cystic Fibrosis)
• Publications

Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis Discover. Prevent. Cure. Abstract Rationale: The ...

• Wal-yan Respiratory Research Centre
• Projects
• AREST CF (Cystic Fibrosis)
• Publications

Transcriptional cofactors of the ETO family are recurrent fusion partners in acute leukemia. We characterized the ETO2 regulome by integrating transcriptomic and chromatin binding analyses in human erythroleukemia xenografts and controlled ETO2 depletion models. We demonstrate that beyond its well-established repressive activity, ETO2 directly activates transcription of MYB, among other genes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

The transition to motherhood, although joyous, can be highly stressful, and the availability of professional postpartum support for mothers is often limited. Peer volunteer support programs may offer a viable and cost-effective method to provide community-based support for new mothers. The aim of this study is to determine the feasibility of a peer volunteer support program-The Mummy Buddy Program-in which experienced volunteer mothers are paired with, and trained to offer social support to, first-time mothers. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

These findings suggest that genetic variants at the VDR locus may play a role in acute wheeze/asthma severity in children ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

An estimated 14 million cases of Plasmodium vivax malaria were reported from Asia, Central and South America, and the Horn of Africa. The clinical burden of vivax malaria is largely driven by its ability to form dormant liver stages (hypnozoites) that can reactivate to cause recurrent episodes of malaria. Elimination of both the blood and liver stages of the parasites ("radical cure") is required to achieve a sustained clinical response and prevent ongoing transmission of the parasite. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

The proportion of 25(OH)D3 that undergoes epimerization is greater with oral vitamin D3 supplementation than exposure to UVR in mice, but not in humans ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• February 2019

To assess the effects of topical antibiotics for people with chronic suppurative otitis media. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Patterns of early childhood developmental vulnerabilities may provide useful indicators for particular mental disorder outcomes in later life ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

his study aimed to determine how carer distress and psychological morbidity change over time following a patient's diagnosis of high-grade glioma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017