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        Research

        Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL

        GATA3low ETP-ALL is a novel stem cell-like leukemia with implications for the use of myeloid-derived therapies ...

        Research

        Factors relating to pregnancy and birth and the risk of childhood brain tumors: Results from an Australian case-control study

        Childhood brain tumors (CBT) are the leading cause of cancer death in children, yet their causes are largely known. This study investigated the association... ...

        Research

        Hepatic sinusoidal obstruction syndrome during chemotherapy for childhood medulloblastoma: Report of a case and review of the literature

        Rishi Sury Nick Kotecha Gottardo RS NG MB ChB (Hons) MRCPCH FRACP PhD MBChB FRACP PhD Co-Head, Leukaemia Translational Research Co-Head, Brain Tumour ...

        Research

        Pre-natal, clonal origin of t(1;11)(p32;q23) acute lymphoblastic leukemia in monozygotic twins

        Investigation of this rare mixed lineage leukemia cytogenetic abnormality aims to provide further evidence of the genetic changes that underpin this leukemia. ...

        Research

        Bilateral murine tumor models for characterizing the response to immune checkpoint blockade

        This protocol describes bilateral murine tumor models that display a symmetrical yet dichotomous response to immune checkpoint blockade ...

        Research

        Precision-guided treatment in high-risk pediatric cancers

        Recent research showed that precision medicine can identify new treatment strategies for patients with childhood cancers. However, it is unclear which patients will benefit most from precision-guided treatment. ...

        Research

        Efficacy of acute myeloid leukemia therapy without stem-cell transplantation in a child with blastic plasmacytoid dendritic cell neoplasm

        Our case demonstrates that AML therapy, without HSCT, can be sufficient to treat this rare disease in children. ...

        Research

        Exploring the immune microenvironment and investigating novel immunotherapeutics for medulloblastoma and paediatric high-grade glioma

        Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research ...

        Research Assistant – Oncogenic Signalling Laboratory

        The Opportunity The Oncogenic Signalling Laboratory is a collaborative group composed of clinical and lab-based researchers focused on the goal of ...

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        Dr Emily Fletcher

        Senior Research Fellow ...

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