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        Research

        Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

        The mutant Der p 2 had altered structure and reduced ability to stimulate pro-inflammatory responses and to bind IgE ...

        Research

        Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific

        Chronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear ...

        Research

        Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)

        Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm. ...

        Research

        Nasal airway epithelial repair after very preterm birth

        Nasal epithelial cells from very preterm infants have a functional defect in their ability to repair beyond the first year of life, and failed repair may be associated with antenatal steroid exposure. ...

        Research

        UV exposure and protection against allergic airways disease

        Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity. ...

        Research

        WA Epithelial Research Program for Childhood Respiratory Diseases

        Anthony Stephen Kicic Stick A SM BSc (Hons) PhD MB BChir PhD MRCP FRACP Rothwell Family Fellow; Head, Airway Epithelial Research Head, P4 Respiratory ...

        Research

        Identification and characterization of a dendritic cell precursor in parenchymal lung tissue

        This is the first study to describe a pulmonary precursor cell for dendritic cells in lung tissue ...

        Research

        Antibody and cell-mediated immunity to pertussis 4 years after monovalent acellular pertussis vaccine at birth

        In the longest reported follow-up of infants who received aP vaccine at birth, we found a trend to lower PT IgG antibodies post booster compared with receipt... ...

        Research

        Quantitation of IgE Binding to the Chitinase and Chitinase-Like House Dust Mite Allergens

        The prevalence of IgE binding to the group 15 and 18 house dust mite (HDM) allergens of the Dermatophagoides species... ...

        Research

        Immune function during early adolescence positively predicts adult facial sexual dimorphism in both men and women

        Our results support a fundamental assumption that facial sexual dimorphism is an indicator of immune function during the development of facial sexual dimorphism ...

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