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        Research

        Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

        Systems biology and innovative data integration can provide fresh insights into the molecular ontogeny of the first week of life ...

        Research

        Trends and predictors of extreme preterm birth: Western Australian population-based cohort study

        First study to show that the increase in extreme preterm birth in high-income jurisdiction is no longer evident after medical terminations and birth defects are excluded ...

        Research

        Concurrent developmental course of sleep problems and emotional/behavioral problems in childhood and adolescence as reflected by the dysregulation profile

        Findings provide evidence for a strong association in the development of sleep problems and difficulties of dysregulation with emotion, cognition, and aggression ...

        Research

        Upper Airway Cell Transcriptomics Identify a Major New Immunological Phenotype with Strong Clinical Correlates in Young Children with Acute Wheezing

        Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes ...

        Research

        Antibody persistence and booster response in adolescents and young adults 4 and 7.5 years after immunization with 4CMenB vaccine

        A more robust immune response after booster compared to a first dose in vaccine-naïve individuals, showed effective priming in an adolescent/young adult population ...

        Research

        Children with East Asian-Born Parents Have an Increased Risk of Allergy but May Not Have More Asthma in Early Childhood

        Children of East Asian ancestry born in Australia have a higher burden of most allergic diseases in the first 6 years of life, whereas asthma may follow a different pattern ...

        Research

        Evening and night work schedules and children's social and emotional well-being

        The findings show that both mothers’ and fathers’ evening and night work schedules are linked to an increase in children's externalizing and internalizing behavior ...

        Research

        Air trapping in early cystic fibrosis lung disease-Does CT tell the full story?

        Mosaic attenuation on expiratory chest computed tomography (CT) is common in early life cystic fibrosis (CF) and often referred to as "air trapping" ...

        Research

        Dose-Banding of Intravenous Piperacillin-Tazobactam in Pediatric Surgical Inpatients

        Dosing errors are the most commonly reported medication error in children. Dosing is often prescribed per weight or based on body area. ...

        Research

        An integrated expression atlas of miRNAs and their promoters in human and mouse

        We provided a broad atlas of miRNA expression and promoters in primary mammalian cells, establishing a foundation for detailed analysis of miRNA. ...

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